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FDA Approves HGH

By Marc Kaufman Washington Post Staff Writer

Saturday, July 26, 2003

FDA Approves Wider Use of Human Growth Hormone

The use of human growth hormone to treat children who are healthy but unusually short was approved yesterday by the Food and Drug Administration -- the first time that the agency has embraced use of the controversial drug to treat unexplained shortness. To advocates of the approval, it offers new possibilities for very small children who suffer from a growth disorder. But critics have attacked the expanded use as a misguided effort to turn a cosmetic or social problem into a medical one.
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The FDA based its decision on studies that found the biosynthesized hormone Humatrope added between one and three inches in height to children who took it for four to six years, and that there were no significant health risks for the children. The drug has been available since the late 1980s, but it had been approved by the FDA only for shortness caused by specific diseases and syndromes. The new approval is for shortness -- defined as an adult height of less than 5 feet 3 inches for men and 4 feet 11 inches for women -- without a known cause.
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